Cerebral atrophy in the behavioral variant of frontotemporal dementia predicts clinical progression

Takeaway

  • In the behavioral variant of frontotemporal dementia, visual atrophy scales enhance the diagnostic certainty of underlying frontotemporal lobar degeneration.

Why this matters

    Although atrophy on magnetic resonance imaging supports the diagnosis of the behavioral variant of frontotemporal dementia, its diagnostic potential is hampered by poor reproducibility. These novel findings suggest that visual atrophy scales, widely available in clinical practice, increase diagnostic certainty of underlying frontotemporal lobar degeneration.