The two clinical phenotypes of migraine with aura, pure visual auras and complex neurological auras, have common and distinct morpho-functional features of nodes in the thalamo-cortical network.
Why this matters
It has been suggested that migraine with aura is a heterogeneous condition where different pathophysiological mechanisms underlie the continuum in clinical phenotype.
This novel study captured the magnetic resonance imaging (MRI) functional hemodynamics of the cortex at rest to quantify functional connectivity.
Better understanding of the underlying differences between the two subtypes of migraine with aura could ultimately lead to better, more targeted interventions.