Summary Summary Short summary of a recent publication, written by scientific experts.

Dilated perivascular spaces, cognitive decline and incident dementia

Takeaway

  • Severe periventricular space (PVS) pathology is a marker for increased cognitive decline and dementia risk, independent of other small vessel disease (SVD) markers.

Why this matters

  • PVS are seen in the basal ganglia (BG) and centrum semiovale (CSO) in older adults, and may be associated with discrete pathophysiology, and potentially, impairments in different cognitive domains.

    • PVS pathology may constitute a potentially important biomarker for early dementia diagnosis, subtyping and prognosis, and may have a significant impact on individualized treatment; as such, further research of PVS etiology and sequelae is required.

International Medical Press is a global provider of independent medical education. Its mission is to provide healthcare professionals with high-quality, trusted medical information with the aim of helping optimize patient care.

No responsibility is assumed by International Medical Press for any injury and/or damage to persons or property through negligence or otherwise, or from any use or operation of any methods, products, instructions, or ideas contained in the material herein. Because of rapid advances in the medical sciences, International Medical Press recommends that independent verification of diagnoses and drug dosages should be made. The opinions expressed do not reflect those of International Medical Press or the sponsor. International Medical Press assumes no liability for any material contained herein.

Learn more

Cognition Dementia Imaging Cognitive decline Magnetic resonance imaging Basal ganglia Centrum semiovale Dilated perivascular spaces