Evolution of the human connectome and development of schizophrenia

Takeaway

  • Evolutionary changes in organization of the human connectome are associated with patterns of schizophrenia dysconnectivity.

Why this matters

  • The genetic and human-specific nature of schizophrenia suggests an evolutionary basis for the disorder.

  • Examining the evolutionary changes associated with schizophrenia facilitates understanding of its biological background and development in humans.