Examining the link between gut microbiota and AD

New findings suggest that gut microbiota (GMB) functional dynamics could be a potential biomarker of Alzheimer’s disease (AD) and neurodegeneration.

Specialists from centers in Milan, Italy, and Geneva, Switzerland, analyzed stool and blood samples collected from 72 older people with different levels of cognitive performance, including dementia.

They used a variety of methods, including sequencing and flow cytometry immunoassays, to determine the bacterial composition of the fecal samples and measure blood levels of lipopolysaccharide (LPS), short chain fatty acids (SCFAs), acetate, propionate, valerate, butyrate, and circulating adhesion molecules.