Neurologic conditions in children and adolescents with COVID-19 or multisystem inflammatory syndrome

Takeaway

  • Neurologic involvement, mostly transient, was common in children and adolescents hospitalized with COVID-19 or multisystem inflammatory syndrome; life-threatening neurologic involvement was rare, being associated with severe inflammation and outcome.

Why this matters

  • A range of neurologic conditions have been reported in adult patients with COVID-19.

  • In pediatric patients, life-threatening neurologic involvement has been reported with multisystem inflammatory syndrome in children (MIS-C), a severe condition associated with COVID-19.

  • The spectrum of neurologic involvement in children and adolescents hospitalized with acute COVID-19 remains unclear.